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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP9B
All Species:
33.33
Human Site:
S229
Identified Species:
61.11
UniProt:
O43861
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43861
NP_940933.3
1147
129304
S229
R
G
K
V
Q
V
K
S
S
D
I
Q
V
G
D
Chimpanzee
Pan troglodytes
XP_001143568
1108
125190
S209
E
K
N
Q
R
I
P
S
D
M
V
F
L
R
T
Rhesus Macaque
Macaca mulatta
XP_001087804
1147
129161
S229
R
G
K
V
Q
V
K
S
S
D
I
Q
V
G
D
Dog
Lupus familis
XP_855968
1147
129093
S228
R
G
K
V
Q
V
K
S
S
D
I
Q
V
G
D
Cat
Felis silvestris
Mouse
Mus musculus
P98195
1146
128999
S228
R
G
K
V
Q
V
K
S
S
D
I
Q
V
G
D
Rat
Rattus norvegicus
NP_001099600
1147
129160
S229
R
G
K
V
Q
V
K
S
S
D
I
Q
V
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509503
1195
134451
S273
R
G
K
V
Q
V
K
S
S
D
I
Q
V
G
D
Chicken
Gallus gallus
XP_417508
1115
125396
S220
R
G
T
V
K
V
K
S
S
N
I
Q
V
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038619
1108
125101
S209
R
T
S
E
K
T
G
S
C
F
I
R
T
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396589
1276
146194
V359
G
F
D
T
P
E
L
V
P
S
S
K
L
R
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799223
1105
125600
S210
T
G
L
V
K
V
P
S
S
E
L
Q
V
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P98205
1107
124818
D210
R
L
F
P
P
F
I
D
N
D
V
C
S
L
T
Baker's Yeast
Sacchar. cerevisiae
P40527
1151
130199
L226
L
S
S
Y
I
V
P
L
A
F
V
L
T
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
98.5
92.5
N.A.
93.2
93
N.A.
87.1
70
N.A.
81.7
N.A.
N.A.
55.6
N.A.
60.7
Protein Similarity:
100
96.4
99.3
96.4
N.A.
97
97.1
N.A.
91.8
81.3
N.A.
88.9
N.A.
N.A.
70.9
N.A.
76.8
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
100
80
N.A.
20
N.A.
N.A.
0
N.A.
53.3
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
33.3
N.A.
N.A.
13.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.9
65
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
8
8
54
0
0
0
8
62
% D
% Glu:
8
0
0
8
0
8
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
8
8
0
0
8
0
0
0
16
0
8
0
0
0
% F
% Gly:
8
62
0
0
0
0
8
0
0
0
0
0
0
54
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
8
0
0
0
62
0
0
0
0
% I
% Lys:
0
8
47
0
24
0
54
0
0
0
0
8
0
0
0
% K
% Leu:
8
8
8
0
0
0
8
8
0
0
8
8
16
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% N
% Pro:
0
0
0
8
16
0
24
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
47
0
0
0
0
0
0
62
0
0
8
% Q
% Arg:
70
0
0
0
8
0
0
0
0
0
0
8
0
16
0
% R
% Ser:
0
8
16
0
0
0
0
77
62
8
8
0
8
8
0
% S
% Thr:
8
8
8
8
0
8
0
0
0
0
0
0
16
0
24
% T
% Val:
0
0
0
62
0
70
0
8
0
0
24
0
62
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _